SILPAKORN UNIVERSITY JOURNAL OF SOCIAL SCIENCES, HUMANITIES, AND ARTS, Vol. 3 (Number 1-2) 2003

Chemistry of Pectin and Its Pharmaceutica Uses : A Review

Pornsak Sriamornsak




Abstract


Pectin, a naturally occurring polysaccharide, has in recent years
gained increasingly in importance. The benefits of natural pectin are
also more and more appreciated by scientists and consumer due to
its biodegradability. Pectin is the methylated ester of polygalacturonic
acid. It is commercially extracted from citrus peels and apple
pomace under mildly acidic conditions. Pectins are divided into two
major groups on the basis of their degree of esterification. The
association of pectin chains leads to the formation of the threedimensional
networks that is to gel formation. The pectin, by itself
or by its gelling properties, was employed in pharmaceutical
industry, health promotion and treatment. It has been used
potentially as a carrier for drug delivery to the gastrointestinal tract,
such as matrix tablets, gel beads, film-coated dose form. This
review will discuss the important chemistry and general properties
of pectin, and its gel formation mechanism and properties. The
example of the pharmaceutical uses of pectin will be given.

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